Angiotensin II modulates glomerular capillary permselectivity in rat isolated perfused kidney.

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Angiotensin II modulates glomerular capillary permselectivity in rat isolated perfused kidney.

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We used a modification of the isolated perfused rat heart, in which coronary effluent and interstitial transudate were separately collected, to investigate the localization and production of angiotensin II (Ang II) in the heart. During combined renin (0.7 to 1.5 pmol Ang I/mL per minute) and angiotensinogen (6 to 12 pmol/mL) perfusion (4 to 8 mL/min) for 60 minutes (n=3), the steady-state level...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 1996

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.v75653